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Close-up image of a semaglutide injection pen with a droplet forming at the needle tip.

Semaglutide Diet: The Best Foods to Eat on Semaglutide

Prescribed for people with Type 2 diabetes since 2017, semaglutide helps people with diabetes regulate their blood sugar and can sometimes aid in weight loss efforts. The medication works by mimicking GLP-1, a hormone that our bodies secrete naturally. GLP-1 is made in our gut and signals when we're full after eating, helping reduce blood sugar levels after meals.

Your stomach empties more slowly when taking semaglutide, a process known as gastric emptying. Some people may experience indigestion from slower digestion as well. If you already experience stomach distress after eating certain foods before you begin taking the medication, you should also avoid or reduce these foods while taking semaglutide.

What is the Semaglutide Diet?

Experts don't generally recommend a specific "semaglutide diet," because each person is different and reacts differently to various foods. Instead, they tend to make broad dietary recommendations that focus on nutrition quality and essential macro- and micro-nutrients.

In your weight loss journey, prioritizing whole, minimally processed, and nutrient-dense foods can help you stay on track and reduce the likelihood of gastrointestinal side effects.

Dietary Recommendations

Your appetite will be less while taking semaglutide, and you will be digesting food more slowly. Both factors affect what types of foods you should focus on. With a lower appetite, you will be eating smaller quantities and should focus on foods that are dense in nutrients, including lean protein, foods rich in probiotics like yogurt and sauerkraut, whole grains like oats, and healthy broth.

To preserve muscle mass during weight loss, make sure your protein intake is sufficient at every meal. Eggs, fish, and legumes are excellent sources of proteins that are easy to digest, and GLP-1 protein bars can help keep your protein intake up on-the-go.

Limit highly processed foods and try to stay away from sugary drinks, including soda, sweetened tea, juice, and energy drinks, which may contribute to spikes in blood sugar.

Additionally, stay hydrated, and support good blood sugar control with sufficient fiber. Drinking plenty of water also helps regulate digestion and can ease mild side effects like constipation. Keep portion sizes small, and consider a GLP-1-friendly snack to help manage hunger between meals. Cold, unsweetened beverages like herbal tea or water can aid digestion and reduce nausea.

Glass of water on a restaurant table.

Focusing on foods that provide a lot of nutrition in a modest portion size, avoiding ultra-processed foods, and getting sufficient fiber will help you to lose weight while maintaining good blood sugar control and meeting your weight loss goals.

Does Semaglutide Cause Stomach Problems?

Stomach problems can occur while taking semaglutide, particularly bloating, belching, and heartburn. Some people also may have stomach pain, nausea, diarrhea, or constipation. GLP-1 medications like semaglutide slow down digestion, which is the main source of the discomfort that people can experience.

Avoiding fried foods, greasy foods, and spicy foods (especially if they previously caused discomfort) can help minimize symptoms during treatment.

Most people who take semaglutide and experience stomach problems say that the side effects may last a few weeks. If the problems last or are severe, consult a doctor or healthcare provider for advice.

Foods to Eat on Semaglutide

Nutritious foods are a must when taking semaglutide. With a reduced appetite, the foods you eat will be important for your overall nutrition and health.

  • Fruits and vegetables: Most fruits and vegetables are great to eat while taking semaglutide, but starchy vegetables and high-fiber veggies like broccoli and cabbage can cause digestive distress.

  • Whole grains: Choose complex carbohydrates like brown rice, quinoa, and steel-cut oats. These are digested more slowly and help stabilize blood sugar levels.

  • Lean protein: Skinless chicken breast, fish, and lean beef are all good options for a semaglutide diet.

  • Healthy fats: You'll find healthy fats in oily fish like salmon, nuts, and avocado. Olive oil, eggs, and even chia seeds all contain healthy fats. Even dark chocolate (in moderation) contains healthy fat.

  • Low-fat dairy: Focus on low-fat dairy foods, including milk and plain cottage cheese and yogurt. Greek yogurt, in particular, is excellent for protein and can be sweetened with fruit.

Toast topped with sliced medium-boiled eggs, avocado, fresh spinach, and herbs.

Choosing a balanced diet that includes a mix of macro- and micronutrients is key to long-term success.

Foods to Avoid on Semaglutide

Experts advise that if you had trouble eating certain foods before you started taking semaglutide (for example, pepperoni pizza), these foods are likely to continue to give you gastric distress while taking semaglutide. Some examples of foods to limit or skip include:

  • High-fat foods: Fried chicken, greasy cheeseburgers, potato chips.

  • High-sugar foods: candy, sweetened sodas, and juice.

  • Refined carbohydrates: cookies, cakes, and pastries.

  • High glycemic index foods: white bread, breakfast cereals, instant oatmeal

Other foods that can cause digestive upset while taking semaglutide include spicy dishes and sauces, alcohol, and caffeine, including coffee and green tea.

Additional Tips to Help You Succeed

  • Until your body adjusts to semaglutide, it's a good idea to eat bland foods and drink plenty of water.

  • Having regular, small meals throughout the day can reduce discomfort.

  • Pay close attention to food choices and mealtimes that work best for you.

If you have any questions about mealtimes, portion sizes, and dietary choices, consult a registered dietitian or your healthcare provider for feedback and guidance.

Key Takeaways for Eating on Semaglutide

If you had problems digesting certain foods before you started taking semaglutide, chances are that these foods will continue to be troublesome while you're taking the medication. Eating small meals spaced throughout the day and avoiding high-fat foods, greasy foods, and high-calorie refined carbohydrates like cookies, pies, and cakes can also help your diet provide you with the nutrition you need without upsetting your system.

Adopting a healthy diet rich in nutrient-dense foods and low in added sugar can support digestion, improve satiety, and contribute to lasting success during your weight loss journey.

Supporting Your Weight Loss Journey

As you adjust to semaglutide, focusing on nutrition, consistency, and mindful habits can make a real difference in your results and how you feel day to day. From managing side effects to hitting your goals, having the right support system matters.

At Nutmeg State Nutrition, we're here to support every step of your GLP-1  journey. Browse our collection of nutrient-rich, high-protein foods and drinks that align with the dietary needs of those using GLP-1s. Whether you're just starting out or fine-tuning your routine, having convenient, diet-friendly options on hand can help you stay on track and feel your best.

With the right tools and a plan that works for your body, healthy, sustainable weight loss is within reach.

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Frequently Asked Questions

How Fast Can I Lose 20lbs on Semaglutide?

Clinical trials show that semaglutide, combined with healthy lifestyle changes, can lead to significant weight loss over time. While individual results vary, many participants in studies lost over 15% of their body weight within about 16 months. Speak with your healthcare provider to understand what’s realistic for you.

How to Maximize Weight Loss on Semaglutide?

People taking semaglutide should follow a nutritious, reduced-calorie diet and increase their physical activity to maximize weight loss.

What is the Best Diet While on Semaglutide?

The best diet while on semaglutide is one that works for you. Semaglutide gives people the opportunity to make diet and lifestyle changes by slowing digestion and increasing your body's natural hormonal signals that you're full after eating. Avoiding problem foods and adding nutritious, easy-to-digest foods will build the best semaglutide diet for you.

Can You Drink Coffee on Semaglutide?

Caffeine can upset digestion, but if you can tolerate it, yes, you can drink coffee while taking semaglutide.

Is Cheese Okay to Eat on Semaglutide?

Cheese is a high-fat, calorically dense food, but you can eat cheese within a nutritious diet while on semaglutide. Just be aware that the high-fat content and milk proteins in cheese may cause indigestion because your stomach is emptying more slowly.

Are Eggs Good to Eat on Semaglutide?

Eggs are a good source of protein and can be part of a nutritious semaglutide diet, especially when balanced with other lean protein sources.

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